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Declarations regarding conflicts of interest can also be collected via the Conflicts of Interest: Author A has received research grants from Company A. or [6] (pp. The journal reserves the right to ask authors to provide signed forms if necessary.The editors will require that the benefits potentially derived from any research causing harm to animals are significant in relation to any cost endured by animals, and that procedures followed are unlikely to cause offense to the majority of readers. Animals (Scientific Procedures) Act, 1986 and associated guidelines, EU Directive 2010/63/EU for animal experiments, or the National Institutes of Health guide for the care and use of Laboratory animals (NIH Publications No. Alternatively, you may provide a detailed justification of why informed consent is not necessary. In such cases the approved Stage 2 manuscript will be accepted for publication, and authors can propose additional experiments for Stage 1 consideration. 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