Black suggests it is a key early touchstone for the series that "truly kickstarts the mythology Sydney and Dixon go on a dangerous case in Morocco involving the safety of the United Commerce Organization and an agent friend of Sydney's dies of a gunshot. Sydney is sent to Greece to retrieve information about new weapons that are being produced by a young tycoon. A drawing of a woman who bears an eerie resemblance to her appears in a blank page of the manuscript thanks to the revealing substance in the vial that McKenas Cole had tried to steal from SD-6. Sydney and Dixon are sent on a dangerous case involving the safety of the United Commerce Organization. Black describes it as "a first episode which superbly establishes both the cast and narrative structure of a show which will, right from the off, attempt to pull a trick many other series would baulk at – long-form, serialised storytelling with regular, daring cliffhangers and a sense of momentum building to bigger personal revelations. Sydney is heavily questioned by the FBI concerning her past and her current activities at SD-6. Francie gets suspicious about Charlie and spies on him. Directed by Ken Olin. With Jennifer Garner, Ron Rifkin, Michael Vartan, Bradley Cooper. Not yet willing to believe that Sydney (Jennifer Garner) is the mole in his operation, sinister SD-6 boss Sloane (Ron Rifkin) sets a trap that he hopes will determine Syd's loyalty once and for all.

Vaughn goes to Colombia to get information about Russian assassin known under the codename "Snowman" whose recent mission was to kill Kjasinau, a.k.a. Dixon's life is at stake after the mission that went wrong.

Department of Special Research gained interest in Sydney's role involving the page 47 and they began their own investigation regarding it. Watch Alias: Mea Culpa from Season 1 at TVGuide.com. Alias (TV Series 2001–2006) cast and crew credits, including actors, actresses, directors, writers and more.

Sloane must take a difficult decision in order to get to the Alliance's council. With Jennifer Garner, Ron Rifkin, Michael Vartan, Bradley Cooper. Meanwhile, Sloane promises Sydney to help her find her mother and Jack is losing his mind because of it.

On her first mission as a double agent, Sydney is sent to Moscow to retrieve some stolen files about nuclear bomb. Meanwhile, Will continues to grow obsessed with Danny's death and starts his own investigation even though Sydney asked him not to. "Sydney returns to SD-6 as a double agent and is assigned with Reviewer A. J. Sloane and Alliance representative Alain Christophe come to conclusion that SD-6 has mole(s) and plan a trap. In the meantime, as he was about to quit his work on a story, Will Tippin gets an unexpected push to continue from the third party. All in the same time, Sydney learns some shocking news about Francie's fiancé, Jack tries to be a better father to Sydney and Will begins his journey in discovering SD-6. Sydney's father, Jack, also tells her the truth about his work and she, enraged, seeks help from real CIA and is hired as their double agent under the command of Agent Vaughn. She and Vaughn set up fake transaction for a Rambaldi artifact with Satk, but their job is compromised when Sloane sends SD-6 agents to steal the presumed second vial. However, after losing Vaughn when the lab exploded, she is in for a surprise... After she manages to escape a certain death at SD-6 and still manages to maintain her cover as double agent, Sydney is sent on a private island to find new identity of Ineni Hassan, an ex weapon smuggler and previous head of weapons resources of SD-6.

Francie is having a rat problem in her house and gives an inspiring speech about catching them which gives Sydney idea how to catch Khasinau. Once the rescue op has been launched, in her quest to prove her innocence, Sydney shocks even her usually unflappable father when she makes a chilling discovery that may unravel the mystery of the 500-year-old prophecy –- she finds proof that Rambaldi's writings may hold more truth about an alleged weapon of mass destruction—and the fate of her own family. SD-6 goes after Will when he comes too close. The circle of Sydney's friends, consisting of Francie, Charlie and Will, begins to suffer from her little white lies about her job in a bank and the many sudden trips she has to make.